BzATP triethylammonium salt

Biochemicals / Biochem-Molecular Biology

-20°C

Highly Purified

Photoaffinity label for ATPase; also P2X7 agonist and P2X1/P2Y1 partial agonist. Prototypic P2X7 receptor agonist (EC50 values are 3.6, 7 and 285 uM for rat, human and mouse receptors respectively). Exhibits 5 - 10 fold greater potency than ATP. Exhibits partial agonist activity at P2X1 (pEC50 = 8.7) and P2Y1 receptors and can be used as a photoaffinity label for ATPase.

This compound is a mixture of isomers

Synonyms:
2ʹ(3ʹ)-O-(4-Benzoylbenzoyl)adenosine-­5ʹ-triphosphate tri(triethylammonium) salt, P2X7 Purinergic Receptor Agonist, BZATP, 2 , 3 -O-(4-benzoylbenzoyl)ATP, P2X Purinergic Receptor Agonist, BZATP

CAS No:
112898-15-4

Molecular Formula:
C24H24N5O15P3.C18H45N3

Molecular Weight:
1018.97

Purity:
≥95%

Appearance:
Colorless liquid

Method for Determining Identity:
Mass Spectrometric Analysis

Solubility:
H₂O (supplied pre-dissolved at a concentration of 5mM)

Storage and Stability:
Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.