Physostigmine hemisulfate

Blue Ice

648, 77

White to off-white solid

Physostigmine Hemisulfate is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor obtained from the Calabar bean, used to treat glaucoma and delayed gastric emptying.

Synonyms:
(3aS-cis)-1, 2, 3, 3a, 8, 8a-Hexahydro-1, 3a, 8-trimethyl-pyrrolo[2, 3-b]indol-5-ol Methylcarbamate (Ester) Sulfate (Salt); Eserine hemisulfate

CAS No:
64-47-1

Molecular Formula:
C₃₀H₄₄N₆O₈S

Molecular Weight:
648.77

Appearance:
White to off-white solid

Purity:
≥98% (HPLC)

Melting Point:
>94ºC (dec.)

Solubility:
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)

Storage and Stability:
Store at 4°C. Hygroscopic. Under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.