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Description: NSC319726 is a novel and potent p53(R175) mutant reactivator with with potential anticancer activity. It exhibits growth inhibition in cells expressing mutant p53 (IC50 of 8 nM for p53(R175) mutant) but shows no inhibition for p53 wild-type cells.
References: Cancer Cell. 2012 May 15; 21(5):614-25.
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