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NSC 207895

NSC 207895

Item no.	V0041-10mg
Manufacturer	InvivoChem LLC
CASRN	58131-57-0
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0041CAS #:58131-57-0Purity >=98% Description: NSC 207895 is a novel anticancer agent that is able to suppress MDM2 with an IC50 of 2.5 uM, which leads to enhanced p53 stabilization/activation and DNA damage. It is therefore a p53 activator that also regulates MDM2, an E3 ligase. NSC 207895 is a benzofuroxan derivative and is less toxic. NSC 207895 decreases the activity of MDMX promoter and subsequently decreases both the mRNA and protein levels of MDMX in MCF-7 cells. This inhibition of MDMX is accompanied with the activation of p53. References: Mol Cancer Ther. 2011 Jan; 10(1):69-79.
Molecular Weight (MW)	279.25
Formula	C11H13N5O4
CAS No.	58131-57-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 0.4 mg/mL (1.43 mM)
	Water:< 1 mg/mL (slightly soluble or insoluble)
	Ethanol: < 1 mg/mL
Synonyms	NSC-207895, NSC207895, XI-006, XI 006, XI006, NSC 207895, NSC179940, NSC-179940, NSC 179940

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 9/4/2025

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