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Nutlin-3b

Nutlin-3b

Item no.	V0043-10mg
Manufacturer	InvivoChem LLC
CASRN	675576-97-3
Amount	10 mg
Quantity options	100 mg 1 mg 250 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0043CAS #:675576-97-3 Purity >=98% Description: Nutlin-3b, a less active/inactive isomer of nutlin-3, is a novel antagonist or inhibitor of p53/MDM2 (murine double minute 2) protein protein interaction with IC50 value of 13.6 uM. It is 150-fold less potent than Nutlin-3 in comparison with Nutlin-3a. Description: References: Proc Natl Acad Sci U S A. 2006 Feb 7; 103(6):1888-93. Mol Cancer Ther. 2006 Feb; 5(2):411-7. References: Related CAS: 890090-75-2; 548472-68-0 (Nutlin-3); 675576-98-4 (Nutlin-3a)
Molecular Weight (MW)	581.49
Formula	C30H30Cl2N4O4
CAS No.	675576-97-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (172.0 mM)
	Water:< 1 mg/mL (slightly soluble or insoluble)
	Ethanol: 100 mg/mL (172.0 mM)
Synonyms	Nutlin3b; Nutlin 3b; Nutlin-3b
Chemical Name	2-Piperazinone, 4-[[(4R, 5S)-4, 5-bis(4-chlorophenyl)-4, 5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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