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ML346 (CID-767276)

ML346 (CID-767276)

Item no.	V0090-500mg
Manufacturer	InvivoChem LLC
CASRN	100872-83-1
Amount	500 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0090CAS #:100872-83-1 Purity >=98% Description: ML346 (CID767276) is a novel and potent activator of heat shock protein 70 (Hsp70) (EC50 = 4600 nM in HeLa cell toxicity assay). ML346 belongs to the barbituric acid class of compounds that induce HSF-1-dependent chaperone expression and restores protein folding in conformational disease models. References: https://www.ncbi.nlm.nih.gov/books/NBK148494/
Molecular Weight (MW)	272.26
Formula	C14H12N2O4
CAS No.	100872-83-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 10mM
	Water: N/A
	Ethanol: N/A
Chemical Name	(E)-5-(3-(4-methoxyphenyl)allylidene)pyrimidine-2, 4, 6(1H, 3H, 5H)-trione
Synonyms	ML-346; ML 346; ML346; CID-767276; CID767276; CID 767276
SMILES Code	O=C(NC(NC/1=O)=O)C1=C\C=C\C2=CC=C(OC)C=C2

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 mg

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Delivery expected until 11/6/2025

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