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Description: TG100-115 is a novel, potent and selective PI3Kgamma/delta inhibitor with potential cardioprotecting effects. It inhibits PI3Kgamma/delta with IC50 of 83 nM/235 nM respectively, and has little effect on PI3Kalpha/beta.
References: Proc Natl Acad Sci U S A. 2006 Dec 26; 103(52):19866-71; J Pharmacol Exp Ther. 2009 Mar; 328(3):758-65.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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