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Description: Sodium orthovanadate, an inorganic compound with chemical formula of Na3VO4, is a potent inhibitor for several enzymes such as protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. It displayed a variety of biological activities, partly due to its structural mimics of phosphates. The inhibitory effects against the aforementioned enzymes can be reversed by dilution or the addition of Ethylenediaminetetraacetic acid (EDTA).
References: J Cereb Blood Flow Metab. 2001 Nov; 21(11):1268-80; J Pharmacol Sci. 2005 Jul; 98(3):205-11.
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