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Description: Bikinin (also known as Abrasin), a pyridinylamido compound, is a novel, potent, non-steroidal and ATP-competitive inhibitor of Arabidopsis GSK-3 (Glycogen synthase kinase 3). It also acts as an activator of brassinosteroid (BR) signaling. Glycogen synthase kinase 3 (GSK3) is a key regulator in signalingpathways in both animals and plants. Three Arabidopsis thaliana GSK3sare shown to be related to brassinosteroid (BR) signaling.
References: Mol Cells. 2014 Nov; 37(11):795-803; Proc Natl Acad Sci U S A. 2014 Jul 1; 111(26):9651-6.
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