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HTH-01-015

HTH-01-015

Item no.	V0250-25mg
Manufacturer	InvivoChem LLC
CASRN	1613724-42-7
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0250CAS #:1613724-42-7Purity >=98% Description: HTH-01-015 is a novel, potent and selective inhibitor of NUAK1( (NUAK family SnF1-like kinase-1) which can serve as useful chemical probes to delineate the biological roles of the NUAK kinases. It inhibits NUAK1 with an IC50 of ca.100 nM, and exhibits > 100-fold higher selectivity for NUAK1 over NUAK2 (IC50 of > 10 uM). The NUAK1 and NUAK2 are members of the AMPK (AMP-activated protein kinase) family of protein kinases that are activated by the LKB1 (liver kinase B1) tumour suppressor kinase. Description: Description: HTH-01-015 is a novel, potent and selective inhibitor of NUAK1( (NUAK family SnF1-like kinase-1) which can serve as useful chemical probes to delineate the biological roles of the NUAK kinases. It inhibits NUAK1 with an IC50 of ca.100 nM, and exhibits > 100-fold higher selectivity for NUAK1 over NUAK2 (IC50 of > 10 uM). The NUAK1 and NUAK2 are members of the AMPK (AMP-activated protein kinase) family of protein kinases that are activated by the LKB1 (liver kinase B1) tumour suppressor kinase. References: Biochem J. 2014 Jan 1; 457(1):215-25; Biochem J. 2014 Jul 15; 461(2):233-45. References: References:

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 11/6/2025

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