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Mocetinostat (MGCD0103)

Mocetinostat (MGCD0103)

Item no.	V0259-25mg
Manufacturer	InvivoChem LLC
CASRN	726169-73-9
Amount	25 mg
Quantity options	100 mg 10 mg 1 g 250 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0259CAS #:726169-73-9Purity >=98% Description: Mocetinostat (formerly MGCD-0103 or MG-0103), is a potent, benzamide-based and orally bioavailable Class I-selective inhibitor of human histone deacetylases (HDAC) with potentianl anticancer activities. Mocetinostat inhibits class I HDACs such as HDAC1/2/3 and class IV (e.g. HDAC11) with IC50s of 0.15 umol/L, 0.29 umol/L, 1.66 umol/L, and 0.59 umol/L respectively, exhibits little/no inhibition aganist class II HDACs (HDAC4-8). It is currently undergoing clinical trials for treating various types of cancers including follicular lymphoma, Hodgkin's lymphoma and acute myelogenous leukemia. Description: References: Mol Cancer Ther. 2008 Apr; 7(4):759-68; Circ Res. 2012 Mar 2; 110(5):739-48. References: Related CAS #: 726169-73-9 (free base); 944537-89-7 (HBr)
Molecular Weight (MW)	396.44
Formula	C23H20N6O
CAS No.	726169-73-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 13 mg/mL (32.8 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	30% PEG400+0.5% Tween80+5% propylene glycol: 30mg/mL
Synonyms	MG0103; MG-0103; MG 0103; MGCD0103; MGCD 0103; MGCD-0103

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 9/4/2025

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