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Belinostat (PXD101; PX105684; NSC726630)

Belinostat (PXD101; PX105684; NSC726630)

Item no.	V0260-1g
Manufacturer	InvivoChem LLC
CASRN	414864-00-9
Amount	1 g
Quantity options	100 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0260CAS #:414864-00-9Purity >=98% Description: Belinostat (formerly PXD-101; PX-105684; NSC-726630; trade name Beleodaq) is a novel, potent and selective HDAC (histone deacetylase) inhibitor with high anticancer activity. It was approved by FDA in 2014 to treat peripheral T-cell lymphoma. Belinostat inhibits HDACs with IC50 of 27 nM in a cell-free assay. Description: References: Mol Cancer Ther. 2003; 2(8):721-8; Mol Cancer Ther. 2006; 5(8):2086-95; Mol Cancer Ther. 2007; 6(1):37-50. References: Related CAS #: 866323-14-0; 414864-00-9
Molecular Weight (MW)	318.35
Formula	C15H14N2O4S
CAS No.	866323-14-0; 414864-00-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 64 mg/mL (201.0 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	2% DMSO+30% PEG 300+ddH2O: 10mg/mL
Synonyms	NSC726630; NSC-726630; PX-105684; PXD 101; PXD101; PXD-101; PX105684; PX 105684; NSC-726630; Trade name: Beleodaq.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 g

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Delivery expected until 11/6/2025

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