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RGFP966

RGFP966

Item no.	V0272-50mg
Manufacturer	InvivoChem LLC
CASRN	1357389-11-7
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0272CAS #:1357389-11-7Purity >=98% Description: RGFP966 (RGF-P966) is a novel, potent and highly selective inhibitor of HDAC3 (histone deacetylase 3) with potential anticancer activity. It inhibits HDAC3 with an IC50 of 80 nM in cell-free assay, exhibits > 200-fold selectivity for HDAC3 over other HDACs. Description: References: Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):2647-52; PLoS One. 2013 Jul 22; 8(7):e68915. References:
Molecular Weight (MW)	362.4
Formula	C21H19FN4O
CAS No.	1357389-11-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 72 mg/mL (198.7 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	1% DMSO+30% polyethylene glycol+1% Tween 80: 30 mg/mL
Other info	Synonym: RGFP966; RGFP-966; RGFP 966 Chemical Name: (E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide InChi Key: BLVQHYHDYFTPDV-VCABWLAWSA-N InChi Code: InChI=1S/C21H19FN4O/c22-18-9-10-20(19(23)13-18)25-21(27)11-8-17-14-24-26(15-17)12-4-7-16-5-2-1-3-6-16/h1-11, 13-15H, 12, 23H2, (H, 25, 27)/b7-4+, 11-8+ SMILES Code: O=C(NC1=CC=C(F)C=C1N)/C=C/C2=CN(C/C=C/C3=CC=CC=C3)N=C2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 9/4/2025

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