Comparison

Iniparib (SAR240550; BSI201; NSC746045; IND71677)

Item no. V0303-100mg
Manufacturer InvivoChem LLC
CASRN 160003-66-7
Amount 100 mg
Quantity options 10 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0303CAS #:160003-66-7Purity >=98%

Description: Iniparib (SAR-240550; BSI-201; NSC-746045; IND-71677) is a novel, potent, and irreversible inhibitor of PARP1 poly(ADP-ribose) polymerase-1 with potential anticancer activity. It demonstrated high efficacy and effectiveness in triple-negative breast cancer (TNBC), and was the first putative PARP inhibitor to start phase III clinical trials but discontinued due to disppointing results. Iniparib has a broad-spectrum of antiproliferative activity against various cancer cells, including drug resistant cell lines.

Description:

References: Biochem Pharmacol. 1995 Aug 25; 50(5):705-14; Biochem Pharmacol. 2002 Feb 1; 63(3):455-62; Clin Cancer Res. 2012 Jan 15; 18(2):510-23.

References:
Molecular Weight (MW)
292.03
Formula
C7H5IN2O3
CAS No.
160003-66-7
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 58 mg/mL (198.6 mM)
Water: < 1 mg/mL
Ethanol: 28 mg/mL (95.9 mM)
Other info
Chemical Name: 4-iodo-3-nitrobenzamide
InChi Key: MDOJTZQKHMAPBK-UHFFFAOYSA-N
InChi Code: InChI=1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H, (H2, 9, 11)
SMILES Code: O=C(N)C1=CC=C(I)C([N+]([O-])=O)=C1
Synonyms

NSC-746045, IND-71677; BSI-201; BSI201; BSI 201; NSC746045; NSC-746045; NSC 746045; ND-71677; NIBA; INO-2BA; SAR-240550; SAR 240550; SAR240550; IND-71677; IND 71677; IND71677; Iniparib;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
available

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