RG108

Item no.	V0405-25mg
Manufacturer	InvivoChem LLC
CASRN	48208-26-0
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0405CAS #:48208-26-0Purity >=98% Description: RG108, also known as N-Phthalyl-L-tryptophan, is a novel non-nucleoside inhibitor of DNA methyltransferase ((DNMT) with potential antitumor activity. It inhibits DNMT with an IC50 of 115 nM in a cell-free assay. Description: References: Cancer Res. 2005 Jul 15; 65(14):6305-11; Bioconjug Chem. 2006 Mar-Apr; 17(2):261-6; PLoS One. 2011; 6(8):e23667. References:
Molecular Weight (MW)	334.33
Formula	C19H14N2O4
CAS No.	48208-26-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 67 mg/mL (200.4 mM)
	Water:< 1 mg/mL
	Ethanol: 67 mg/mL (200.4 mM)
Other info	Chemical Name: (S)-2-(1, 3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)propanoic acid. InChi Key: HPTXLHAHLXOAKV-INIZCTEOSA-N InChi Code: InChI=1S/C19H14N2O4/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15/h1-8, 10, 16, 20H, 9H2, (H, 24, 25)/t16-/m0/s1 SMILES Code: O=C(O)[CH](CC1=CNC2=CC=CC=C12)N3C(C4=CC=CC=C4C3=O)=O
Synonyms	N-Phthalyl-L-tryptophan; RG-108; RG 108; RG108;

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Amount: 25 mg

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