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SB202190 (FHPI)

SB202190 (FHPI)

Item no.	V0478-100mg
Manufacturer	InvivoChem LLC
CASRN	152121-30-7
Amount	100 mg
Quantity options	1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0478CAS #:152121-30-7Purity >=98% Description: SB-202190 (known also as SB202190; FHPI) is a novel, highly selective, potent and cell-permeable inhibitor of p38 MAPK with potential antiseptic activity. It inhibits p38alpha/beta with IC50s of 50 nM/100 nM in cell-free assays. n the endotoxin model of sepsis, SB202190 treatment produces a statistically significant survival benefitcompared with control. Description: n the endotoxin model of sepsis, SB202190 treatment produces a statistically significant survival benefitcompared with control. References: Biochem J. 2000 Oct 1; 351(Pt 1):95-105; Proc Natl Acad Sci U S A. 2006 Aug 22; 103(34):12855-60; J Surg Res. 2009 Mar; 152(1):46-53. References:
Molecular Weight (MW)	331.34
Formula	C20H14N3OF
CAS No.	152121-30-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 66 mg/mL (199.2 mM)
	Water: < 1 mg/mL
	Ethanol: 12 mg/mL (36.2 mM)
Solubility (In vivo)	1% DMSO+30% polyethylene glycol+1% Tween 80: 30 mg/mL
Synonyms	FHPI; SB-202190; SB202190; SB202190 Chemical Name: 4-(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol SMILES Code: OC1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 9/4/2025

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