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ENMD-2076 Tartrate

ENMD-2076 Tartrate

Item no.	V0528-500mg
Manufacturer	InvivoChem LLC
CASRN	1291074-87-7
Amount	500 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0528CAS #:1291074-87-7Purity >=98% Description: ENMD-2076 Tartrate, the tartrate salt of ENMD-981693 (MKC-1693), is a novel, potent and orally bioactive multi-kinase inhibitor with potential antineoplastic activity. It inhibits Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, shows 25-fold selectivity for Aurora A over Aurora B, and is less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRalpha. ENMD-2076 shows potent anti-proliferative activity in vitro and high in vivo antitumor efficacy. Description: References: Mol Cancer Ther. 2011 Jan; 10(1):126-37; 17(24):7614-24; Br J Haematol. 2010 Aug; 150(3):313-25. References: Related CAS #: 1291074-87-7 (tartrate); 934353-76-1 (free base); 1453868-32-0 (tartrate)
Molecular Weight (MW)	525.56
Formula	C25H31N7O6
CAS No.	1291074-87-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (190.3 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	30% PEG400+0.5% Tween80+5% propylene glycol: ca.30 mg/mL
Synonyms	ENMD2076 tartrate; ENMD2076; ENMD 2076; ENMD-2076.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 mg

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