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PD173955

PD173955

Item no.	V0676-50mg
Manufacturer	InvivoChem LLC
CASRN	260415-63-2
Amount	50 mg
Quantity options	100 mg 10 mg 1 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0676CAS #:260415-63-2Purity >=98% Description: PD173955 (PD-173955), a src-selective tyrosine kinase inhibitor, is a novel and potent Bcr-Abl inhibitor with potential anticancer activity. It inhibits Bcr-Abl with an IC50 of 1-2 nM, it also inhibits Src activity with IC50 of 22 nM. Description: References: Cancer Res. 2002 Aug 1; 62(15):4244-55; Cancer Res. 1999 Dec 15; 59(24):6145-52. References:
Molecular Weight (MW)	443.35
Formula	C21H16Cl2N4OS
CAS No.	260415-63-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 15 mg/mL (33.8 mM)
	Water:< 1 mg/mL
	Ethanol:< 1 mg/mL
Other info	Chemical Name: 6-(2, 6-dichlorophenyl)-8-methyl-2-((3-(methylthio)phenyl)amino)pyrido[2, 3-d]pyrimidin-7(8H)-one InChi Key: VAARYSWULJUGST-UHFFFAOYSA-N InChi Code: InChI=1S/C21H16Cl2N4OS/c1-27-19-12(9-15(20(27)28)18-16(22)7-4-8-17(18)23)11-24-21(26-19)25-13-5-3-6-14(10-13)29-2/h3-11H, 1-2H3, (H, 24, 25, 26) SMILES Code: O=C1C(C2=C(Cl)C=CC=C2Cl)=CC3=CN=C(NC4=CC=CC(SC)=C4)N=C3N1C
Synonyms	PD 173955; PD173955; PD-173955

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Amount: 50 mg

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