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Mardepodect (PF-2545920; MP-10)

Mardepodect (PF-2545920; MP-10)

Item no.	V0792-100mg
Manufacturer	InvivoChem LLC
CASRN	898562-94-2
Amount	100 mg
Quantity options	10 mg 250 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0792CAS #:898562-94-2Purity >=98% Description: Mardepodect (formerly known as PF-2545920, PF2545920, MP10; MP-10) is a novel, potent and selective PDE10A (phosphodiesterase) inhibitor with antipsychotic activity. It inhibits PDE10A with an IC50 of 0.37 nM, and shows > 1000-fold selectivity for PDE10A over other isoforms of PDE. It is potentially useful for the treatment of schizophrenia. Description:antipsychotic activity. It inhibits PDE10A References: J Pharmacol Exp Ther. 2009 Nov; 331(2):574-90; J Med Chem. 2009 Aug 27; 52(16):5188-96. References: Related CAS: 1292799-56-4
Molecular Weight (MW)	392.45
Formula	C25H20N4O
CAS No.	898562-94-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 78 mg/mL (198.8 mM)
	Water:< 1 mg/mL
	Ethanol: 78 mg/mL (198.8 mM)
SMILES	CN1N=C(C2=CC=C(OCC3=NC4=CC=CC=C4C=C3)C=C2)C(C5=CC=NC=C5)=C1
Synonyms	Mardepodect; PF-2545920; PF 2545920; MP-10; MP10; MP 10; PF2545920; Chemical Name: 2-(4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxymethyl)quinoline InChi Key: AZEXWHKOMMASPA-UHFFFAOYSA-N InChi Code: InChI=1S/C25H20N4O/c1-29-16-23(18-12-14-26-15-13-18)25(28-29)20-7-10-22(11-8-20)30-17-21-9-6-19-4-2-3-5-24(19)27-21/h2-16H, 17H2, 1H3 SMILES Code: CN1N=C(C2=CC=C(OCC3=NC4=CC=CC=C4C=C3)C=C2)C(C5=CC=NC=C5)=C1

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Amount: 100 mg

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Delivery expected until 9/4/2025

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