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Fenspiride HCl

Fenspiride HCl

Item no.	V0798-50g
Manufacturer	InvivoChem LLC
CASRN	5053-08-7
Amount	50 g
Quantity options	10 g 1 g 25 g 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0798CAS #:5053-08-7Purity >=98% Description: Fenspiride (NAT-333; JP-428; NDR-5998A; Decaspiride; Espiran; trade names Eurespal, Pneumorel), an oxazolidinone spiro compound acting as a alpha adrenergic and H1 histamine receptor antagonist, is a bronchodilator with potent anti-inflammatory properties. Iit inhibits phosphodiesterase 4/3 (PDE4/3) with logIC50 values of 4.16 and 3.44, respectively, in human isolated bronchi. Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. Description: References: Eur J Pharmacol. 1998 Jan 2; 341(1):79-86; Eur J Pharmacol. 1993 Jul 6; 238(1):47-52. References: Related CAS#: 5053-06-5 (free base); 5053-08-7 (HCl)
Molecular Weight (MW)	296.79
Formula	C15H20N2O2.HCl
CAS No.	5053-08-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 59 mg/mL (198.8 mM)
	Water:< 1 mg/mL
	Ethanol: 9 mg/mL (30.3 mM)
Other info	Chemical Name: 8-(2-Phenylethyl)-1-oxa-3, 8-diazaspiro(4.5)decan-2-one hydrochloride InChi Key: FIKFLLIUPUVONI-UHFFFAOYSA-N InChi Code: InChI=1S/C15H20N2O2.ClH/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13; /h1-5H, 6-12H2, (H, 16, 18); 1H SMILES Code: O=C1OC2(CCN(CCC3=CC=CC=C3)CC2)CN1.[H]Cl
Synonyms	NAT333; NAT 333; JP 428; JP428; NDR-5998A; NDR 5998A; NAT-333; JP-428; NDR5998A; Decaspiride; Espiran; Fenspiride HCl; Fenspiride hydrochloride; Fluiden. trade names Eurespal, Pneumorel

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