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Description: Naringin (also known as Naringoside; AI319008; Aurantiin; AI3-19008), a flavanone-7-O-glycoside, is a novel, potent, natural flavanone glycoside found in citrus fruits (e.g. tomatoes and grapefruits). It exerts a wide range of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of cytochrome P450 enzymes. It inhibits hepatic P-glycoprotein (P-gp) and some drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions.
References: Life Sci. 1999; 65(24):2591-602; J Nutr. 2006 Jun; 136(6):1477-82.
Chemical Name: 7-(((2S, 3R, 4S, 5S, 6R)-4, 5-dihydroxy-6-(hydroxymethyl)-3-(((2S, 3R, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one
InChi Key: DFPMSGMNTNDNHN-JJLSSNRUSA-N
InChi Code: InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7, 10, 16, 18, 20-30, 32-36H, 8-9H2, 1H3/t10-, 16?, 18+, 20-, 21+, 22+, 23-, 24+, 25+, 26-, 27+/m0/s1
SMILES Code: O=C1CC(C2=CC=C(O)C=C2)OC3=C1C(O)=CC(O[CH]4[CH]([CH]([CH]([CH](CO)O4)O)O)O[CH]5[CH]([CH]([CH]([CH](C)O5)O)O)O)=C3
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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