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Tanshinone I (Tanshinone A)

Tanshinone I (Tanshinone A)

Item no.	V0843-500mg
Manufacturer	InvivoChem LLC
CASRN	568-73-0
Amount	500 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0843CAS #:568-73-0Purity >=98% Description: Tanshinone I (Tanshinone A; dihydrotanshinone, tanshinone IIA), a natural pigment isolated from the herbal medicine Salvia miltiorrhiza Bunge, is a potent inhibitor of type IIA human recombinant sPLA2 with important biological activity. It inhibits type IIA human recombinant sPLA2 and rabbit recombinant cPLA2 with IC50s of 11 uM and 82 uM, respectively. It is an active component that may have anticancer, antidiabetic, and neuroprotective properties. Tanshinone I displays cytotoxicity against human macrophages and IFN-g production in KLH-primed lymph node cells. Tanshinone I inhibits PGE2 formation from LPS-induced RAW macrophages (IC50 = 38 uM). Description: References: Phytother Res. 2002 Nov; 16(7):616-20; Carcinogenesis. 2008 Oct; 29(10):1885-92. References:
Molecular Weight (MW)	276.29
Formula	C18H12O3
CAS No.	568-73-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 23 mg/mL (83.2 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 1, 6-dimethyl-phenanthro[1, 2-b]furan-10, 11-dione InChi Key: AIGAZQPHXLWMOJ-UHFFFAOYSA-N InChi Code: InChI=1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H, 1-2H3 SMILES Code: O=C(C1=C2C(C(C)=CC=C2)=CC=C1C3=C4C(C)=CO3)C4=O
Synonyms	dihydrotanshinone, tanshinone I, or tanshinone IIA

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 mg

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