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Benidipine HCl

Benidipine HCl

Item no.	V0885-500mg
Manufacturer	InvivoChem LLC
CASRN	91599-74-5
Amount	500 mg
Quantity options	100 mg 1 g 250 mg 2 g 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0885CAS #:91599-74-5Purity >=98% Description: Benidipine HCl (formerly SC-278724, KW-3049 HCl; trade names Sular; Coniel) is the hydrochloride salt form of benidipine which is a DHP/dihydropyridine calcium channel blocker/CCB with anti-hypertensive activity. It has been approved for the treatment high blood pressure and angina pectoris. It also inhibits aldosterone-induced MCR activation. In addition, benidipine Hydrochloride has been reported to reduce oxidative stress. Benidipine is sold in the United States under the proprietary name Sular. References: Methods Find Exp Clin Pharmacol. 2005 Apr; 27(3):167-71; J Cardiovasc Pharmacol. 1999 Aug; 34(2):248-53. Related CAS #: 91599-74-5 (HCl); 105979-17-7 (free base);
Molecular Weight (MW)	542.02
Formula	C28H31N3O6.HCl
CAS No.	91599-74-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 8 mg/mL (14.8 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	Chemical Name: 3-((R)-1-benzylpiperidin-3-yl) 5-methyl (R)-2, 6-dimethyl-4-(3-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate hydrochloride InChi Key: KILKDKRQBYMKQX-MIPPOABVSA-N InChi Code: InChI=1S/C28H31N3O6.ClH/c1-18-24(27(32)36-3)26(21-11-7-12-22(15-21)31(34)35)25(19(2)29-18)28(33)37-23-13-8-14-30(17-23)16-20-9-5-4-6-10-20; /h4-7, 9-12, 15, 23, 26, 29H, 8, 13-14, 16-17H2, 1-3H3; 1H/t23-, 26-; /m1./s1 SMILES Code: O=C(C1=C(C)NC(C)=C(C(O[CH]2CN(CC3=CC=CC=C3)CCC2)=O)[CH]1C4=CC=CC([N+]([O-])=O)=C4)OC.[H]Cl
Synonyms	KW-3049; KW3049; Coniel; Benidipine Hydrochloride; KW 3049;

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Amount: 500 mg

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