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Dapoxetine HCl (LY-210448 HCl)

Dapoxetine HCl (LY-210448 HCl)

Item no.	V0977-10g
Manufacturer	InvivoChem LLC
CASRN	129938-20-1
Amount	10 g
Quantity options	100 mg 1 g 250 mg 25 mg 2 g 500 mg 50 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0977CAS #:129938-20-1Purity >=98% Description: Dapoxetine HCl (formerly known as LY210448; LY-210448; trade name Priligy), an antidepressant, is a novel, potent, short-acting and selective serotonin reuptake inhibitor (SSRI) that has alto been used for the treatment of premature ejaculation. It is a short-acting novel selective serotonin reuptake inhibitor marketed for the treatment of premature ejaculation in men. Granisetron blocks the delayed rectifier current (IK) of feline isolated ventricular myocytes with a KD of 4.3 mM. Granisetron shows an intrinsic voltage-dependence as the block increases with depolarization. Description: References: Neuropharmacology. 2012 Jun; 62(7):2261-6; Naunyn Schmiedebergs Arch Pharmacol. 2012 Jul; 385(7):707-16. References: Related CAS: 119356-77-3 (free base)
Molecular Weight (MW)	341.87
Formula	C21H23NO.HCl
CAS No.	129938-20-1 (HCl);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 68 mg/mL (198.9 mM)
	Water: < 1 mg/mL
	Ethanol: 68 mg/mL (198.9 mM)
SMILES Code	CN(C)[CH](CCOC1=C2C=CC=CC2=CC=C1)C3=CC=CC=C3.[H]Cl
Synonyms	LY-210448; Dapoxetine HCl; LY 210448; LY210448; Priligy

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