Comparison

Amitriptyline HCl (Elavil)

Item no. V0992-50g
Manufacturer InvivoChem LLC
CASRN 549-18-8
Amount 50 g
Quantity options 100 g 10 g 25 g
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V0992CAS #:549-18-8Purity >=98%

Description: Amitriptyline (Elavil; Tryptanol; Amitriptylin; Damilen; Triptanol), a tricyclic antidepressant (TCA), is an inhibitor of serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with potential anti-depressive activity. It inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50s of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.

Description:

References: Chem Biol. 2009 Jun 26; 16(6):644-56

References:

Related CAS #: 549-18-8 (HCl); 50-48-6 (free base)

Molecular Weight (MW)
313.86
Formula
C20H23N.HCl
CAS No.
549-18-8
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 63 mg/mL (200.7 mM)
Water: 15 mg/mL (47.8 mM)
Ethanol: 63 mg/mL (200.7 mM)
Solubility (In vivo)

Chemical Name: 3-(10, 11-dihydro-5H-dibenzo[a, d][7]annulen-5-ylidene)-N, N-dimethylpropan-1-amine hydrochloride

InChi Key: KFYRPLNVJVHZGT-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20; /h3-6, 8-12H, 7, 13-15H2, 1-2H3; 1H

SMILES Code: CN(C)CC/C=C1C2=CC=CC=C2CCC3=CC=CC=C\13.[H]Cl

Synonyms
trade names: Elavil; Amitriptylin; Tryptanol; Damilen; Triptanol; Amitriptyline HCl; Amitriptyline hydrochloride;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 g
Available: In stock
available

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