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Description: Loxapine Succinate (Loxapac; Adasuve; Cloxazepin; Daxolin; Oxilapine), the succinate salt of Loxapine which is a dibenzoxazepine anti-psychotic drug, is a potent D2DR/D4DR inhibitor as well as serotonergic receptor antagonist. It is a typical antipsychotic agent primarily used for the treatment of schizophrenia.
References: Eur Neuropsychopharmacol. 2005 Jan; 15(1):23-30; Psychiatry Res. 1984 Aug; 12(4):277-85.
Related CAS#: 1977-10-2
Chemical Name: butanedioic acid; 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1, 4] benzoxazepine
InChi Key: YQZBAXDVDZTKEQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H18ClN3O.C4H6O4/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18; 5-3(6)1-2-4(7)8/h2-7, 12H, 8-11H2, 1H3; 1-2H2, (H, 5, 6)(H, 7, 8)
SMILES: CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.C(CC(=O)O)C(=O)O
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