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Celecoxib (SC 58635)

Celecoxib (SC 58635)

Item no.	V1038-10g
Manufacturer	InvivoChem LLC
CASRN	169590-42-5
Amount	10 g
Quantity options	1 g 250 mg 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1038CAS #:169590-42-5Purity >=98% Description: Celecoxib (formerly SC58635; YM-177; SC-58635; YM 177; trade name Celebrex; Xilebao), an anti-inflammatory agent of the NSAID class, is a potent and selective COX-2 inhibitor of the non-steroidal anti-inflammatory drug (NSAID) class with an IC50 of 40 nM in Sf9 cells. In vitro, celecoxib not only reduced the production of PGE2 but also inhibited the downstream effects of PGE2. Celecoxib blocked migration and invasion of A549 cells increased by PGE2 in the wound healing and transwell assays. Description: References: J Med Chem. 1997 Apr 25; 40(9):1347-65; Int J Radiat Oncol Biol Phys. 2013 Feb 1; 85(2):472-6. References: Related CAS: 170569-87-6 (Desmethyl Celecoxib)
Molecular Weight (MW)	381.37
Formula	C17H14F3N3O2S
CAS No.	169590-42-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 76 mg/mL (199.3 mM)
	Water: < 1 mg/mL
	Ethanol: 33 mg/mL (86.5 mM)
Solubility (In vivo)	2% DMSO+30% PEG 300+5% Tween 80+ddH2O: 5mg/mL
Synonyms	SC 58635; YM177. Celecoxib; SC58635; YM-177; SC-58635; YM 177; trade name Celebrex; Xilebao.

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