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CTEP (RO4956371)

CTEP (RO4956371)

Item no.	V1084-25mg
Manufacturer	InvivoChem LLC
CASRN	871362-31-1
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1084CAS #:871362-31-1Purity >=98% Description: CTEP (also called RO4956371; RO 4956371; RO-4956371) is a long-acting and orally bioavailable allosteric antagonist of metabotropic glutamate receptor 5 (mGlu5) receptor with important biological activity. It inhibits mGlu5 with an IC50 of 2.2 nM and exhibits > 1000-fold selectivity for mGlu5 over other mGlu receptors. Description: References: J Pharmacol Exp Ther. 2011 Nov; 339(2):474-86; Neuron. 2012 Apr 12; 74(1):49-56. References:
Molecular Weight (MW)	391.77
Formula	C19H13ClF3N3O
CAS No.	871362-31-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 78 mg/mL (199.1 mM)
	Water: < 1 mg/mL
	Ethanol: 10 mg/mL (25.5 mM)
Solubility (In vivo)	30% propylene glycol, 5% Tween 80, 65% D5W: 6 mg/mL
Synonyms	RO-4956371; CTEP; RO4956371; RO 4956371; 2-chloro-4-[2-[2, 5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine Chemical Name: 2-chloro-4-[2-[2, 5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine SMILES Code: FC(F)(F)OC1=CC=C(N2C(C)=C(C#CC3=CC(Cl)=NC=C3)N=C2C)C=C1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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