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Description: Bambuterol HCl (Bambec; Oxeol; KWD-2183l; UNII-Y1850G1OVC), the hydrochloride salt of Bambuterol which is a prodrug of terbutaline, is a potent and long acting beta-adrenoceptor agonist (LABA) that was approved (outside the US) for use in the treatment of asthma. Bambuterol acts as a bronchodilator that inhibits plasma BChE (cholinesterase) during metabolism prolongs suxamethonium-induced neuromuscular blockade.
References: Acta Anaesthesiol Scand. 1990 Oct; 34(7):596-9; EBioMedicine. 2015 Feb 13; 2(4):356-64.
Related CAS#: 81732-65-2 (free base)
Chemical Name: [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N, N-dimethylcarbamate; hydrochloride
InChi Key: LBARATORRVNNQM-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H29N3O5.ClH/c1-18(2, 3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7; /h8-10, 15, 19, 22H, 11H2, 1-7H3; 1H
SMILES Code: CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl
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