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Nebivolol (R 065824)

Nebivolol (R 065824)

Item no.	V1112-50mg
Manufacturer	InvivoChem LLC
CASRN	118457-14-0
Amount	50 mg
Quantity options	100 mg 10 mg 1 g 250 mg 25 mg 500 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1112CAS #:118457-14-0Purity >=98% Description: Nebivolol (R065824; R-065824; Nobiten; Vasoxen) is a potent and selective beta1/beta1-adrenoceptor antagonist with antihypertensive effects. It inhibits beta1-adrenoceptor with an IC50 of 0.8 nM. As a beta blocker, nebivolol has been used to treat high blood pressure and heart failure. Description: References: Mol Pharmacol. 1988 Dec; 34(6):843-51; Circ J. 2008 Apr; 72(4):660-70. References:
Molecular Weight (MW)	441.9
Formula	C22H25F2NO4.HCl
CAS No.	152520-56-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 88 mg/mL (199.1 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 1-((R)-6-fluorochroman-2-yl)-2-(((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol InChi Key: KOHIRBRYDXPAMZ-JJTQDJFQSA-N InChi Code: InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4, 7-10, 17-18, 21-22, 25-27H, 1-2, 5-6, 11-12H2/t17-, 18?, 21-, 22-/m1/s1 SMILES Code: O[CH](CNCC([CH]1CCC2=CC(F)=CC=C2O1)O)[CH]3CCC4=CC(F)=CC=C4O3
Synonyms	R-65824; Nebivolol; R 065824; R065824; Nobiten; Vasoxen

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Amount: 50 mg

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