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Xylometazoline HCl

Xylometazoline HCl

Item no.	V1125-1g
Manufacturer	InvivoChem LLC
CASRN	1218-35-5
Amount	1 g
Quantity options	10 g 25 g 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1125CAS #:1218-35-5Purity >=98% Description: Xylometazoline HCl (xylomethazoline; Otrivine; Amidrin; Balkis; Chlorohist-LA; Decongest; espa-rhin; Gelonasal), the hydrochloride salt of Xylometazoline, is an alpha-adrenoceptor agonist commonly used as nasal decongestant. It exhibits highest potency at alpha2B-adrenoceptor subtype with EC50 of 99 uM. Xylometazoline is an alpha-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at alpha2B-adrenoceptor subtype with EC50 of 99 uM. Xylometazoline binds at adrenoceptor subtypealpha1A, alpha1B, alpha1D, alpha2A, alpha2B, alpha2C with IC50 of 0.08, 0.56, 0.45, 0.98, 1.8, 0.22uM, repectively. Description: References: Fundam Clin Pharmacol. 2010 Dec; 24(6):729-39. References: Related CAS #: 1218-35-5 (HCl) 526-36-3 (free base)
Molecular Weight (MW)	280.84
Formula	C16H24N2.HCl
CAS No.	1218-35-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 27 mg/mL (96.1 mM)
	Water: 56 mg/mL (199.4 mM)
	Ethanol: 56 mg/mL (199.4 mM)
Other info	Chemical Name: 2-[(4-tert-butyl-2, 6-dimethylphenyl)methyl]-4, 5-dihydro-1H-imidazole hydrochloride InChi Key: YGWFCQYETHJKNX-UHFFFAOYSA-N InChi Code: InChI=1S/C16H24N2.ClH/c1-11-8-13(16(3, 4)5)9-12(2)14(11)10-15-17-6-7-18-15; /h8-9H, 6-7, 10H2, 1-5H3, (H, 17, 18); 1H SMILES Code: CC1=C(CC2=NCCN2)C(C)=CC(C(C)(C)C)=C1.[H]Cl
Synonyms	Trade name: Otrivine; Amidrin; Balkis; Chlorohist-LA; Decongest; espa-rhin; Gelonasal.

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