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Prazosin HCl

Prazosin HCl

Item no.	V1137-10g
Manufacturer	InvivoChem LLC
CASRN	19237-84-4
Amount	10 g
Quantity options	100 mg 1 g 250 mg 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1137CAS #:19237-84-4 Purity >=98% Description: Prazosin HCl (Furazosin, cp12299-1; cp-12299-1; Minipress, Peripress), the hydrochloride salt of prazosin, is a potent and competitive alpha-1 adrenoceptor antagonist with antihypertensive effects. It has been used to treat high blood pressure or BPH-benign prostatic hyperplasia, heart failure, hypertension, pheochromocytoma, Raynaud disease, prostratic hypertrophy and urinary retention. Prazosin leads to a significant increase in VEGF concentration in endothelial cells and angiogenesis only if eNOS is present. Prazosin binds to the alpha1-adrenergic receptors that are present on smooth muscle cells surrounding all larger blood vessels. Description: References: Am J Physiol Heart Circ Physiol. 2004 Nov; 287(5):H2300-8; Psychopharmacology (Berl). 2011 Nov; 218(1): 89-99. References: Related CAS#?19216-56-9 (free)
Molecular Weight (MW)	419.86
Formula	C19H21N5O4·HCl
CAS No.	19237-84-4 (HCl);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 4 mg/mL (9.52 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: [4-(4-amino-6, 7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone; hydrochloride InChi Key: WFXFYZULCQKPIP-UHFFFAOYSA-N InChi Code: InChI=1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14; /h3-4, 9-11H, 5-8H2, 1-2H3, (H2, 20, 21, 22); 1H SMILES Code: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl
Synonyms	cp-12299-1; Prazosin Hydrochloride, Prazosin HCl, Furazosin hydrochloride, cp12299-1; cp 12299-1; Minipress, Peripress, Prazosin

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