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Description: Phentolamine Mesylate (OraVerse, Regitine mesylate, Regitine, Regityn, Rogitine, Z-Max), the mesylate/mesilate/methanesulfonate salt of Phentolamine, is a reversible and nonselective alpha-adrenergic receptor antagonist with antihypertensive effects. It has been used for the prevention or control of hypertensive episodes. Phentolamine mesylate displaces binding of the selective alpha 1 receptor antagonists 125IHEAT and 3Hprazosin and the alpha 2 receptor antagonists 3Hrauwolscine and 3HRX 821002 with relatively high affinity in corpus cavernosum membranes.
References: Int J Impot Res. 1998 Dec; 10(4):215-23; Fundam Clin Pharmacol. 2001 Feb; 15(1):1-7.
Chemical Name: 3-(((4, 5-dihydro-1H-imidazol-2-yl)methyl)(p-tolyl)amino)phenol methanesulfonate
InChi Key: OGIYDFVHFQEFKQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15; 1-5(2, 3)4/h2-8, 11, 21H, 9-10, 12H2, 1H3, (H, 18, 19); 1H3, (H, 2, 3, 4)
SMILES Code: CC1=CC=C(C=C1)N(CC2=NCCN2)C3=CC(=CC=C3)O.CS(=O)(=O)O
Phentolamine mesilate, Phentolamine methanesulfonate, OraVerse, Regitine mesylate, Regitine, Regityn, Rogitine, Z-Max, Phentolamine Mesylate,
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