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Tolazoline HCl

Tolazoline HCl

Item no.	V1155-100g
Manufacturer	InvivoChem LLC
CASRN	59-97-2
Amount	100 g
Quantity options	10 g 1 g 25 g 2 g 50 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1155CAS #:59-97-2Purity >=98% Description: Tolazoline HCl (Pridazole, Priscol, Benzalolin, Divascol, Priscoline), the hydrochloride salt of tolazoline, is an imidazolline-based and non-selective competitive alpha-adrenergic receptor antagonist used as a vasodilator for the treatment of spasms of peripheral blood vessels. Tolazoline is a pulmonary vasodilator indicated used to decrease pulmonary vascular resistance (PVR) in persistent pulmonary hypertension of the newborn (PPHN). Tolazoline has moderate alpha-adrenergic blocking activity and has histamine agonist activity. Tolazoline usually reduces pulmonary arterial pressure and vascular resistance. Description: References: J Cardiovasc Pharmacol. 1998 May; 31(5):721-33; Ann Thorac Surg. 2006 Jan; 81(1):125-31. References: Related CAS#: 59-98-3 (free base)
Molecular Weight (MW)	196.68
Formula	C10H12N2.HCl
CAS No.	59-97-2 (HCl salt);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 39 mg/mL (198.3 mM)
	Water: 39 mg/mL (198.3 mM)
	Ethanol: N/A
Other info	IUPAC/Chemical Name: 1H-Imidazole, 4, 5-dihydro-2-(phenylmethyl)-, hydrochloride (1:1) InChi Key: RHTNTTODYGNRSP-UHFFFAOYSA-N InChi Code: InChI=1S/C10H12N2.ClH/c1-2-4-9(5-3-1)8-10-11-6-7-12-10; /h1-5H, 6-8H2, (H, 11, 12); 1H SMILES Code: [H]Cl.C1(CC2=CC=CC=C2)=NCCN1
Synonyms	Tolazoline, Benzalolin, Divascol, Pridazole, Priscol, Priscoline

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