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Diphenhydramine

Diphenhydramine

Item no.	V11731-25g
Manufacturer	InvivoChem LLC
CASRN	58-73-1
Amount	25 g
Quantity options	10 g 1 g 2 g 500 mg 50 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V11731CAS #:58-73-1Purity >=98% Description: DiphenhydramineHCl is a potent and first-generation histamine H1 receptor antagonistand an antiemetic that is used in various allergic conditions such asrhinitis, urticaria and conjunctivitis. Diphenhydramine blockstetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) sodiumcurrents with K(d) values of 48 mM and 86 mM, respectively, at aholding potential of -80 mV. Diphenhydramine shifts theconductance-voltage curve for TTX-S sodium currents in the depolarizingdirection but has little effect on that for TTX-R sodium currents. References: Brain Res. 2000 Oct 27; 881(2):190-8; Oncol Res. 2004; 14(7-8):363-72. Related CAS #:147-24-0 (HCl) 58-73-1 (free base) Description: DiphenhydramineHCl is a potent and first-generation histamine H1 receptor antagonistand an antiemetic that is used in various allergic conditions such asrhinitis, urticaria and conjunctivitis. Diphenhydramine blockstetrodotoxin-sensitive (TTX-S) and tetrodotoxin-resistant (TTX-R) sodiumcurrents with K(d) values of 48 mM and 86 mM, respectively, at aholding potential of -80 mV. Diphenhydramine shifts theconductance-voltage curve for TTX-S sodium currents in the depolarizingdirection but has little effect on that for TTX-R sodium currents. Description: References: Brain Res. 2000 Oct 27; 881(2):190-8; Oncol Res. 2004; 14(7-8):363-72. References: Related CAS #:147-24-0 (HCl) 58-73-1 (free base)

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Amount: 25 g

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