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Description: Aclidinium Bromide (formerly LAS34273, LAS-W 330; brand names Tudorza Genuair; Eklira Genuair; Bretaris Genuair) is a potent, long-acting and inhalable muscarinic antagonist used as a maintenance treatment for chronic obstructive pulmonary disease (COPD). It acts by potently inhibiting human muscarinic acetylcholine receptors-AChR M1, M2, M3, M4 and M5 with Ki values of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.
References: J Pharmacol Exp Ther. 2009 Nov; 331(2):740-51; Eur J Pharm Sci. 2010 Mar 18; 39(5):283-90.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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