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Description: Hexamethonium Bromide (Vegolysen; Esametina; Simpatoblock), a peripherally-acting and nondepolarizing neuromuscular blocker, is a selective antagonist of neuronal-type nicotinic AChR in ganglia that was used to treat chronic hypertension. But the use of Hexamethonium was discontinued due to the non-specificity of its action.
References: Br J Pharmacol. 1984 Mar; 81(3):519-31; Br J Pharmacol. 1997 Nov; 122(6):1025-34.
InChi Key: FAPSXSAPXXJTOU-UHFFFAOYSA-L
InChi Code: InChI=1S/C12H30N2.2BrH/c1-13(2, 3)11-9-7-8-10-12-14(4, 5)6; ; /h7-12H2, 1-6H3; 2*1H/q+2; ; /p-2
SMILES Code: C[N+](CCCCCC[N+](C)(C)C)(C)C.[Br-].[Br-]
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