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Clemastine Fumarate (HS592; Meclastine)

Clemastine Fumarate (HS592; Meclastine)

Item no.	V1207-500mg
Manufacturer	InvivoChem LLC
CASRN	14976-57-9
Amount	500 mg
Quantity options	100 mg 1 g 250 mg 2 g 50 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1207CAS #:14976-57-9Purity >=98% Description: Clemastine Fumarate (HS-592; HS 592 fumarate; Meclastine), the fumarate salt of clemastine, is a first-generation H1 histamine antagonist with anticholinergic and sedative adverse effects. It inhibits H1 histamine receptor with an IC50 of 3 nM. Clemastine is used to relieve hay fever and allergy symptoms such as sneezing; runny nose; and red, itchy, and tearing eyes, also used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus Description: References: Mol Pharmacol. 1992 Aug; 42(2):227-34. References: Related CAS #:15686-51-8 (free base) 14976-57-9 (fumarate)
Molecular Weight (MW)	459.96
Formula	C21H26ClNO.C4H4O4
CAS No.	14976-57-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 35 mg/mL (76.1 mM)
	Water: < 1 mg/mL
	Ethanol:< 1 mg/mL
Solubility (In vivo)	30% propylene glycol, 5% Tween 80, 65% D5W: 5mg/mL
Synonyms	HS-592 fumarate; HS592 fumarate; Meclastine fumarate; HS 592 fumarate;

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Amount: 500 mg

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