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Ranitidine HCl

Ranitidine HCl

Item no.	V1211-5g
Manufacturer	InvivoChem LLC
CASRN	66357-59-3
Amount	5 g
Quantity options	10 g 1 g 250 mg 2 g 500 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1211CAS #:66357-59-3Purity >=98% Description: Ranitidine HCl (ZANTAC; AH-19065; AH 19065; Tanidina; Toriol; Fendibina; Gastridina; Sostril; Zantic; Ranisen), the hydrochloride salt of Ranitidine, is a histamine H2-receptor antagonist with an IC50 of 3.3 +/- 1.4 uM. It is used to treat stomach or intestinal ulcers by inhibiting stomach acid production. Ranitidine HCl sensitizes hepatocytes to killing by cytotoxic products from activated neutrophils, whereas Famotidine lacks this ability. Ranitidine inhibits the production of tumor necrosis factor-alpha (TNF-alpha) in monocytes stimulated with lipopolysaccharide in vitro. Description: References: J Pharmacol Exp Ther. 2003 Oct; 307(1):9-16; J Pharmacol Exp Ther. 2002 Jun; 301(3):1157-65. References: Related CAS #:66357-35-5 (free base) 66357-59-3 (HCl) 71130-06-8 (HCl) 73857-20-2 (Ranitidine-N-oxide)
Molecular Weight (MW)	350.86
Formula	C13H22N4O3S.HCl
CAS No.	66357-59-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 70 mg/mL (199.5 mM)
	Water: 70 mg/mL (199.5 mM)
	Ethanol:< 1 mg/mL
Solubility (In vivo)	Chemical Name: (E)-N-(2-(((5-((dimethylamino)methyl)furan-2-yl)methyl)thio)ethyl)-N'-methyl-2-nitroethene-1, 1-diamine hydrochloride InChi Key: GGWBHVILAJZWKJ-KJEVSKRMSA-N InChi Code: InChI=1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3; /h4-5, 9, 14-15H, 6-8, 10H2, 1-3H3; 1H/b13-9+; SMILES Code: CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C.Cl
Synonyms	AH19065; Ranitidine Hydrochloride; ZANTAC; AH-19065; AH 19065; Tanidina; Toriol; Fendibina; Gastridina; Sostril; Zantic; Ranisen; Ranitidine HCl

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Amount: 5 g

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