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Buclizine HCl (UCB-4445)

Buclizine HCl (UCB-4445)

Item no.	V1226-250mg
Manufacturer	InvivoChem LLC
CASRN	129-74-8
Amount	250 mg
Quantity options	100 mg 1 g 25 mg 2 g 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #: V1226CAS #:129-74-8Purity >=98% Description: Buclizine hydrochloride (AH-2526, UCB 4445; AH2526; UCB-4445, Buclina, Longifene, Posdel, Vibazine), the hydrochloride salt of buclizine which is used for motion sickness, is a piperazine derivative and a sedating antihistamine with antimuscarinic and moderate sedative action. Buclizine has been used in the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness. Additionally, it has been used in the management of vertigo in diseases affecting the vestibular apparatus. Description: References: Profiles Drug Subst Excip Relat Methodol. 2011; 36:1-33. References: Related CAS #: 129-74-8 (HCl) 82-95-1 (free base).
Molecular Weight (MW)	505.95
Formula	C28H33ClN2.2HCl
CAS No.	129-74-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: < 1 mg/mL
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	Chemical Name: 1-(4-(tert-butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride InChi Key: SDBHDSZKNVDKNU-UHFFFAOYSA-N InChi Code: InChI=1S/C28H33ClN2.2ClH/c1-28(2, 3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24; ; /h4-16, 27H, 17-21H2, 1-3H3; 2*1H SMILES Code: ClC1=CC=C(C(N2CCN(CC3=CC=C(C(C)(C)C)C=C3)CC2)C4=CC=CC=C4)C=C1.[H]Cl.[H]Cl
Synonyms	UCB-4445; AH 2526, UCB4445; AH-2526, UCB 4445; AH2526; Buclizine; Buclizine dihydrochloride; AH-2526, UCB 4445; AH2526; UCB-4445, Buclina, Longifene, Posdel, Vibazine.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 9/4/2025

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