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Description: Azatadine dimaleate (SCH10649; SCH-10649; Idulamine; Idulian; Lergocil; Optimine; Zadine), the dimaleate salt of azatadine, is a potent histamine and cholinergic inhibitor that has been approved for treating allergic rhinitis and chronic urticaria. It inhibits histamine and cholinergic receptors with IC50s of 6.5 nM and 10 nM, respectively.
References: Agents Actions. 1974 Oct; 4(4):264-70; Clin Pharmacokinet. 1991 Nov; 21(5):372-93.
Chemical Name: 6, 11-Dihydro-11-(1-methylpiperidin-4-ylidene)-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine dimaleate
InChi Key: SGHXFFAHXTZRQM-SPIKMXEPSA-N
InChi Code: InChI=1S/C20H22N2.2C4H4O4/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19; 2*5-3(6)1-2-4(7)8/h2-7, 12H, 8-11, 13-14H2, 1H3; 2*1-2H, (H, 5, 6)(H, 7, 8)/b; 2*2-1-
SMILES Code: CN1CC/C(CC1)=C2C3=CC=CC=C3CCC4=CC=CN=C4\2.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
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