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benztropine-mesylate

benztropine-mesylate

Item no.	V1248-500mg
Manufacturer	InvivoChem LLC
CASRN	132-17-2
Amount	500 mg
Quantity options	1 g 250 mg 2 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1248CAS #:132-17-2Purity >=98% Description: Benztropine mesylate (NSC-42199; ST-50997629; NSC 42199; ST 50997629; Cogentin; MLS000737056), the mesilate salt of Benztropine, is a highly potent dopamine transporter (DAT) inhibitor used for the treatment of symptoms of Parkinson's disease such as involuntary tremor and dystonia. It inhibits dopamine transporter with an IC50 of 118 nM. Benztropine is a synthetic compound derived from the combination of atropine and diphenhydramine that acts centrally to antagonize M1 muscarinic acetylcholine receptors. Description: References: J Med Chem. 2005 May 5; 48(9):3337-43; Neurology. 1997 Apr; 48(4):1077-81. References:
Molecular Weight (MW)	403.53
Formula	C21H25NO.CH4SO3
CAS No.	132-17-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 50 mg/mL (123.9 mM)
	Water: 81 mg/mL (200.7 mM)
	Ethanol: 81 mg/mL (200.7 mM)
Other info	Chemical Name: (1R, 3r, 5S)-3-(benzhydryloxy)-8-methyl-8-azabicyclo[3.2.1]octane methanesulfonate InChi Key: CPFJLLXFNPCTDW-BWSPSPBFSA-N InChi Code: InChI=1S/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17; 1-5(2, 3)4/h2-11, 18-21H, 12-15H2, 1H3; 1H3, (H, 2, 3, 4)/t18-, 19+, 20+; SMILES Code: CN1[CH]2C[CH](OC(C3=CC=CC=C3)C4=CC=CC=C4)C[CH]1CC2.OS(C)(=O)=O
Synonyms	NSC42199; ST50997629; NSC-42199; ST-50997629; NSC 42199; ST 50997629; Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate; Benztropine Mesylate; Cogentin; Cogentin mesylate; MLS000737056

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Amount: 500 mg

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