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Rotundine

Rotundine

Item no.	V1264-250mg
Manufacturer	InvivoChem LLC
CASRN	483-14-7
Amount	250 mg
Quantity options	100 mg 1 g 25 mg 2 g 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #: V1264CAS #:483-14-7Purity >=98% Description: Rotundine (also called L-THP or L-tetrahydropalmatine) is a naturally occuring alkaloid isolated from Corydalis rhizoma (a traditional Chinese medicinal plant) with analgesic activity. It acts as a potent and selective antagonist of dopamine D1 receptor with an IC50 of 166 nM. Description: References: Future Med Chem. 2012 Feb; 4(2):177-86; Acta Pharmacol Sin. 2005 May; 26(5):533-8. References:
Molecular Weight (MW)	355.43
Formula	C21H25NO4
CAS No.	483-14-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 8 mg/mL (22.5 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (5S)-3, 8-dimethoxy-13-methyl-5, 6, 11, 12-tetrahydro-5, 11-epiminodibenzo[a, e][8]annulene-2, 9-diol InChi Key: JLYWCHLTLCGOMW-LOACHALJSA-N InChi Code: InChI=1S/C19H21NO4/c1-20-14-4-10-6-16(21)19(24-3)9-13(10)15(20)5-11-7-18(23-2)17(22)8-12(11)14/h6-9, 14-15, 21-22H, 4-5H2, 1-3H3/t14?, 15-/m0/s1 SMILES Code: OC1=C(OC)C=C2C(CC3C4=CC(O)=C(OC)C=C4C[C]2([H])N3C)=C1
Synonyms	(-)-Tetrahydropalmatine; L-Tetrahydropalmatine; Rotundine

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Amount: 250 mg

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