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Pergolide Mesylate (LY127809)

Pergolide Mesylate (LY127809)

Item no.	V1268-250mg
Manufacturer	InvivoChem LLC
CASRN	66104-23-2
Amount	250 mg
Quantity options	100 mg 10 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1268CAS #:66104-23-2 Purity >=98% Description: Pergolide Mesylate (Permax; Pergotoliderived; LY127809; LY-127809), the mesylate salt of Pergolide, is a novel and potent antiparkinsonian agent which acts as a dopaminergic agonist. It is used in some countries for the treatment of Parkinson's disease. Pergolide mesylate functions as an agonist at the dopamine D2, D1 and serotonin 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, and 5-HT2C receptors. It may possess agonist activity at other dopamine receptor subtypes as well, similar to cabergoline. Description: References: Science. 1979 Sep 14; 205(4411):1151-3; Br Med J (Clin Res Ed). 1983 Apr 9; 286(6372): 1177–1179. References: Related CAS#: 66104-22-1 (free) 423748-02-1 (mesylate salt)
Molecular Weight (MW)	410.59
Formula	C19H26N2S.CH4O3S
CAS No.	66104-23-2 (mesylate);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mg/mL (24.35 mM)
	Water: 82 mg/mL (199.71 mM)
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 8-beta-((Methylthio)methyl)-6-propylergoline methanesulfonate InChi Key: UWCVGPLTGZWHGS-ZORIOUSZSA-N InChi Code: InChI=1S/C19H26N2S.CH4O3S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21; 1-5(2, 3)4/h4-6, 10, 13, 16, 18, 20H, 3, 7-9, 11-12H2, 1-2H3; 1H3, (H, 2, 3, 4)/t13-, 16-, 18-; /m1./s1 SMILES Code: [H][C]1(N(CCC)C[CH](CSC)C[C]12[H])CC3=CNC4=C3C2=CC=C4.CS(=O)(O)=O
Synonyms	LY127809; Pergolide methanesulfonate; LY-127809; LY 127809

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Amount: 250 mg

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