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Ticlopidine HCl

Ticlopidine HCl

Item no.	V1304-2g
Manufacturer	InvivoChem LLC
CASRN	53885-35-1
Amount	2 g
Quantity options	10 g 1 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1304CAS #:53885-35-1Purity >=98% Description: Ticlopidine HCl (Ticlodix; Ticlodone; 53-32C; 5332C; trade name Ticlid), the hydrochloride salt of ticlopidine, is a potent P2 receptor inhibitor against used as antiplatelet and anticoagulant. It inhibits ADP-induced platelet aggregation with an IC50 of ca.2 uM. Ticlopidine is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor. Initial research showed that Ticlopidine was useful for preventing strokes and coronary stent occlusions. However, due to its serious side effects of neutropenia and thrombotic thrombocytopenic purpura, Ticlopidine was primarily used in patients in whom aspirin was not tolerated, or in whom dual antiplatelet therapy was desirable. Description: References: Clin Pharmacol Ther. 1975 Oct; 18(4):485-90; Thromb Haemost. 1979 Apr 23; 41(2):436-49. References: Related CAS #:CAS#53885-35-1 (HCl) 55142-85-3 (free base).
Molecular Weight (MW)	300.25
Formula	C14H14ClNS.HCl
CAS No.	53885-35-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 1 mg/mL (3.3 mM)
	Water: 4 mg/mL (13.3 mM)
	Ethanol: 1 mg/mL (3.3 mM)
Other info	Chemical Name: 5-(2-chlorobenzyl)-4, 5, 6, 7-tetrahydrothieno[3, 2-c]pyridine hydrochloride InChi Key: MTKNGOHFNXIVOS-UHFFFAOYSA-N InChi Code: InChI=1S/C14H14ClNS.ClH/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14; /h1-4, 6, 8H, 5, 7, 9-10H2; 1H SMILES Code: C1CN(CC2=C1SC=C2)CC3=CC=CC=C3Cl.Cl
Synonyms	Ticlodix; Ticlodone; Ticlopidine; Ticlopidine HCl; 53 32C; 53-32C; 5332C; trade name Ticlid

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Amount: 2 g

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