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suvorexant-mk-4305

suvorexant-mk-4305

Item no.	V1306-50mg
Manufacturer	InvivoChem LLC
CASRN	1030377-33-3
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1306CAS #:1030377-33-3Purity >=98% Description: This is a DEA controlled substance schedule IV Suvorexant (also known as MK-4305) is a potent dual OX receptor antagonist with Ki of 0.55 nM and 0.35 nM for OX1 receptor and OX2 receptor, respectively. Suvorexant is developed by Merck for the treatment of insomnia. It is currently undergoing Phase III trials. Suvorexant works by turning off wakefulness rather than by inducing sleep. As a dual orexin receptor (OXR) antagonist (DORA), suvorexant (MK-4305) has shown promise for the treatmen to finsomnias and sleep disorders. Description: This is a DEA controlled substance schedule IV his is a DEA controlled substance schedule IV References: J Med Chem. 2010 Jul 22; 53(14):5320-32; Br J Pharmacol. 2014 Jan; 171(2):351-63. References:
Molecular Weight (MW)	450.92
Formula	C23H23ClN6O2
CAS No.	1030377-33-3
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mg/mL (22.2 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	4% DMSO+10% PEG 400+10% Tween 80: 5mg/mL
Synonyms	MK4305; MK 4305; MK-4305

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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