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KY02111

KY02111

Item no.	V1354-50mg
Manufacturer	InvivoChem LLC
CASRN	1118807-13-8
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1354CAS #:1118807-13-8Purity >=98% Description: KY02111 (KY 02111; KY-02111) is a potent and selective inhibitor of the Wnt signaling pathway with important biological activity. It promotes the differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, and may also act downstream of APC and GSK3beta. When tested with IMR90-1 hiPSCs transfected with TCF receptor plasmids, KY 02111 (1 uM) significantly reduced luciferase activities in a dose-dependent manner by inhibiting canonical WNT signaling pathway. In cardiac colonies on the day 30, KY 02111 showed that nearly 73%-85% of IMR90-1 hiPSCs expressed the cardiac markers. References: Cell Rep. 2012 Nov 29; 2(5):1448-60.
Molecular Weight (MW)	376.86
Formula	C18H17ClN2O3S
CAS No.	1118807-13-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 75 mg/mL (199.0 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: N-(6-Chloro-2-benzothiazolyl)-3, 4-dimethoxybenzenepropanamide InChi Key: LXFKEVQQSKQXPR-UHFFFAOYSA-N InChi Code: InChI=1S/C18H17ClN2O3S/c1-23-14-7-3-11(9-15(14)24-2)4-8-17(22)21-18-20-13-6-5-12(19)10-16(13)25-18/h3, 5-7, 9-10H, 4, 8H2, 1-2H3, (H, 20, 21, 22) SMILES Code: O=C(NC1=NC2=CC=C(Cl)C=C2S1)CCC3=CC=C(OC)C(OC)=C3
Synonyms	KY02111; KY 02111; KY-02111

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Amount: 50 mg

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