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Description: GW788388 (GW-788388; GW 788388) is an inhibitor of ALK5/TGF-beta type II receptor with potential antifibrotic activity. It inhibits ALK5/TGF-beta type II receptor with an IC50 of 18 nM in a cell-free assay.
References: J Med Chem. 2006 Apr 6; 49(7):2210-21; Kidney Int. 2008 Mar; 73(6):705-15.
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