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Cyclocytidine HCl (Ancitabine)

Cyclocytidine HCl (Ancitabine)

Item no.	V1443-5g
Manufacturer	InvivoChem LLC
CASRN	10212-25-6
Amount	5 g
Quantity options	1 g 250 mg 2 g 500 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1443CAS #:10212-25-6Purity >=98% Description: Cyclocytidine (formerly NSC-145668; Cyclo-C; NSC145668; Ancitabine) is a pyrimidine nucleoside-based prodrug of cytarabine that has to be activated through hydrolysis to cytarabine under in vivo conditions. It acts by inhibiting DNA synthesis and has been used for the treatment of leukemia. Structurally, Cyclocytidine is similar to deoxycytidine and thus can be incorporated into DNA and then kills cancer cells. References: J Pharm Sci. 1984 Jul; 73(7):896-902; Biochem Pharmacol. 1972 Feb 15; 21(4):465-75. References: Related CAS: 31698-14-3 (free base); 10212-25-6 (HCl)
Molecular Weight (MW)	261.66
Formula	C9H12ClN3O4
CAS No.	10212-25-6
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 52 mg/mL (198.7 mM)
	Water: 44 mg/mL (168.2 mM)
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (2R, 3R, 3aS, 9aR)-2-(hydroxymethyl)-6-imino-2, 3, 3a, 9a-tetrahydrofuro[1, 2][1, 3]oxazolo[3, 4-a]pyrimidin-3-ol; hydrochloride InChi Key: KZOWNALBTMILAP-JBMRGDGGSA-N InChi Code: InChI=1S/C9H11N3O4.ClH/c10-5-1-2-12-8-7(16-9(12)11-5)6(14)4(3-13)15-8; /h1-2, 4, 6-8, 10, 13-14H, 3H2; 1H/t4-, 6-, 7+, 8-; /m1./s1 SMILES Code: OC[CH](O1)[CH](O)[CH](OC2=N3)[CH]1N2C=CC3=N.Cl
Synonyms	Ancitabine Cyclo-CMP hydrochloride; NSC 145668; NSC-145668; Cyclo-C; NSC 145668 HCl; Ancitabine HCl; Cyclocytidine HCl; NSC145668;

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Amount: 5 g

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Delivery expected until 10/2/2025

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