« Back
Home /
Hydroxyurea (Hydroxycarbamide)

Hydroxyurea (Hydroxycarbamide)

Item no.	V1464-50g
Manufacturer	InvivoChem LLC
CASRN	127-07-1
Amount	50 g
Quantity options	100 g 10 g 1 g 2 g 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1464CAS #:127-07-1Purity >=98% Description: Hydroxyurea (formerly known as NCI-c04831, NSC-32065; NCIc04831, NSC32065; Biosupressin; Carbamoyl oxime; Droxia; Hydroxycarbamide) is an approved antineoplastic drug that has been used for treating various cancers such as melanoma, sickle-cell disease and resistant chronic myelocytic leukemia. It acts as a cell apoptosis inducer by inhibiting DNA synthesis through the inhibition of ribonucleoside diphosphate reductase. Hydroxyurea can inhibit HIV-1 replication. In vitro experiments have shown that the 90% inhibitory concentration (IC90) of hydroxyurea for laboratory strains of HIV-1 in activated PBMC is 0.4 mM. Description: References: Clin Infect Dis. 2000 Jun; 30 Suppl 2:S193-7; Clin Infect Dis. 2000 Jun; 30 Suppl 2:S143-50. References:
Molecular Weight (MW)	76.05
Formula	CH4N2O2
CAS No.	127-07-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 15 mg/mL (197.2 mM)
	Water: 15 mg/mL (197.2 mM)
	Ethanol: < 1 mg/mL
Other info	Chemical Name: 1-hydroxyurea InChi Key: VSNHCAURESNICA-UHFFFAOYSA-N InChi Code: InChI=1S/CH4N2O2/c2-1(4)3-5/h5H, (H3, 2, 3, 4) SMILES Code: O=C(N)NO
Synonyms	NCI-c04831, NSC-32065; NCI c04831, NSC 32065; NCIc04831, NSC32065; Biosupressin; Carbamoyl oxime; Droxia; Hydroxycarbamide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50 g

available

Delivery expected until 10/2/2025

Express Delivery: Save 16 days

Compare

Add to wishlist

Get an offer